Bleomycin Sulfate

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CERTIFICATE OF ANALYSIS

Bleomycin Sulfate Chemical Compound

PRODUCT: Bleomycin Sulfate, Streptomyces verticillus.
(mixture of Bleomycin A2, B2 & B4)
PRODUCT No.: B526
CAS: 9041-93-4 LOT No.: B-170920
MW: 1397 (for A2) & 1407 (for B2) STORE: +4º C, Protect from Light
RTECS: EC5991990 TOXICITY: Hazardous
Highly Toxic if swallowed: May
cause heritable genetic damage.
FORMULA: C55H84N17O21S3 (for A2)
C55H81N19O21S2 (for B2)
Analysis Specification (USP 31) Results
Appearance White to off-white powder Conforms
Identification Conforms to Standard Conforms
Bleomycin Contents:
A2
B2
B4
.
≥55 – 70%
25 – 32%
≤1%
.
61.0%
31.0%
0.05%
Purity (HPLC) ≥90% (A2 + B2) 92.0%
Copper content ≤0.1% 0.07%
L.O.D. ≤6.0% 2.1%
Potency (USP Bleomycin Units) 1.5 – 2.0 U/mg 1.6 U/mg
PH 4.5 – 6.0 5.8
Solubility Freely Soluble in H2O (20mg/mL) Conforms
Stability Stable at +4º C if desiccated and properly stored for at least 3 years. Stock solution stable for a month at +4º C. Ships ambient.
QUALITY ASSURANCE: Verified upon data received from manufacturer.

FOR RESEARCH or FURTHER PROCESSING – NOT FOR HUMAN or DRUG USE