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CERTIFICATE OF ANALYSIS

| PRODUCT: Daptomycin (Cubicin or LY146032) |
PRODUCT No.: D168 |
| CAS: 103060-53-3 | LOT No.: D-159431601-3 |
| MW: 1620.67 | STORE: +4º C |
| FORMULA: C72H101N17O26 | Country of Origin: China |
| Analysis | Specification | Results |
|---|---|---|
| Appearance | Off-White to Pale Yellow Crystalline Powder | Conforms |
| Identification (1H NMR) | Conforms to Standard | Conforms |
| Purity (HPLC) | ≥>98% | >99.7% |
| Melting Point | Reported | +201 – 202º C |
| Heavy Metals (Pb) Impurities (Single) Impurities (Total) Residual Solvent (Ethanol) Residual Solvent (Isopropanol) |
≤ 20.0 ppm ≤ 2.0% ≤ 8.0% ≤ 5000.0 ppm ≤ 5000.0 ppm |
Conforms Conforms 3.08% Not detected Not detected |
| Water content (K.F.) Bacterial Endotoxins Solubility |
≤10.0% ≤0.5 EU Water, Ethanol, Methanol Clear |
2.86% 0.1 EU Conforms |
| Stability: | Stable at -20º C for at least 2 years. Store dry and protect from light. |
| QUALITY ASSURANCE: | Verified upon data received from supplier. |
FOR RESEARCH or FURTHER PROCESSING – NOT FOR HUMAN or DRUG USE
