Deep learning improves de novo protein-binder design
BioTechniques News Aisha Al-Janabi Using deep learning to enhance physical models for protein-binder design increases the target binding success rate. Researchers at […]
Category: News
AI-powered neural bypass restores movement and sensation in man with paralysis
BioTechniques News Annie Coulson For the first time, researchers have successfully implanted an AI-powered double neural bypass to restore feeling and movement […]
Bursting viruses’ bubbles: new antiviral strategy targets the membrane
BioTechniques News Beatrice Bowlby Disrupting the membrane of viruses offers a novel antiviral approach and could be effective against a variety of […]
Making sure it sticks: mass spectrometry to trace the mechanism of covalent molecular glues
BioTechniques News Aisha Al-Janabi New study reveals how mass spectrometry can be used to determine the mechanisms used by molecular glues to […]
Computer models nanoparticle–protein interactions
BioTechniques News Aisha Al-Janabi A new machine learning model, NeCLAS, can determine whether and how a protein and nanoparticle will bind, which […]
Airway to AirGel: the new in vitro respiratory model
BioTechniques News Beatrice Bowlby A new organoid model platform has been added to the growing arsenal of tools with which to investigate […]
Bacterial swimming machinery – a potential antibiotic target?
BioTechniques News Aisha Al-Janabi New mechanistic insights into the protein complex that powers the bacterial flagellum may assist antibiotic development. A study […]
Cryo-EM reveals new structural elements in a key ciliary protein complex
BioTechniques News Beatrice Bowlby Scientists capture the protein complex responsible for transporting signaling molecules to cilia in unprecedented detail. Using single-particle cryogenic […]
Studying protein–ligand binding with Raman spectroscopy
Studying protein–ligand binding with Raman spectroscopy
The protein–protein interaction promoting Parkinson’s disease
BioTechniques News Aisha Al-Janabi What role do protein–protein interactions play in the accumulation of α-synuclein in the brains of individuals with Parkinson’s […]
Role of ganglia in heart-disease-associated sleep disturbance
BioTechniques News Beatrice Bowlby Researchers report a previously unknown role of ganglia, clusters of nerve cell bodies, in sleep disturbances frequently experienced […]
FDA funds research into first continuous mRNA-manufacturing platform
BioTechniques News Beatrice Bowlby A 3-year research program, funded by the FDA, aims to design the first continuous mRNA-manufacturing platform. Faculty at […]
Sea snakes regain color vision through gene duplication
BioTechniques News Beatrice Bowlby Snakes lost their color vision many millennia ago, but one species of sea snake has regained these genes. […]
Placenta-on-a-chip could revolutionize research into pregnancy-related conditions
BioTechniques News Beatrice Bowlby A placenta-on-a-chip that mimics the workings of the placenta has been developed, allowing further research into the organ […]
Critical role of nSMase2 in HIV replication reveals new antiretroviral target
BioTechniques News Aisha Al-Janabi A new antiretroviral target has been identified that suppresses HIV-1 replication and selectively kills HIV-1-infected cells. A collaboration […]
Structure of enzyme involved in pre-tRNA splicing revealed
BioTechniques News Beatrice Bowlby The structure of a key enzyme involved in protein production is revealed by cryo-electron microscopy (cryo-EM). Using cryo-EM, […]
Works like a CHARM: the AI model that genomically profiles gliomas
BioTechniques News Aisha Al-Janabi AI can now genomically profile brain tumors during surgery, offering real-time guidance on how best to remove or […]
New way to diagnose ovarian cancer with extracellular vesicle membrane proteins
BioTechniques News Beatrice Bowlby Membrane proteins expressed on ovarian cancer-derived extracellular vesicles (EVs) are shown to be suitable biomarkers for ovarian cancer […]
Tiny shrimp has a unique way of organizing cells during embryonic development
BioTechniques News Aisha Al-Janabi The crustacean Parhyale hawaiensis (P. hawaiensis) organizes its cells in a grid-like pattern during embryo development, relying on […]
Learning about cellular senescence from squishy sea creatures
BioTechniques News Aisha Al-Janabi Tiny sea creatures give insights into how the biological processes of healing and aging are intertwined, providing a […]