Tough pill to swallow: the cellular uptake pathway for large drug molecules
BioTechniques News Aisha Al-Janabi How can we improve drug specificity? Larger, more complex drugs may be the way to target ‘undruggable’ cell […]
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Glycans block cholera infection
BioTechniques News Beatrice Bowlby Researchers find that a type of glycan prevents cholera infection by interfering with the microbe’s gene expression. Mucus […]
Revealing the molecular markers of our sixth sense
BioTechniques News Aisha Al-Janabi A new study investigated how proprioceptive sensory neurons (pSNs), the cells underlying the “sixth sense”, function. Can you […]
Oblique plane microscopy captures cell dynamics of whole organisms
BioTechniques News Beatrice Bowlby Researchers developed a large-scale, dynamic imaging technique using mesoscopic oblique plane microscopy, which can capture 3D images of […]
How to: model a heart attack
BioTechniques News Aisha Al-Janabi Researchers from the University of Southern California (CA, USA) have created a model that could one day be […]
RAS gene mutations fuel malignancy through crosstalk with tumor microenvironment
BioTechniques News Aisha Al-Janabi A single oncogenic mutation can hijack mechanisms causing benign tumors to become malignant. A study by researchers […]
Introducing FingerDTA: a new drug discovery framework
BioTechniques News Beatrice Bowlby A new study has shown how machine learning can be used to simulate drug–target binding affinity to identify […]
Seaweed molecules improve synthetic vascular grafts
BioTechniques News Beatrice Bowlby Applying a molecule derived from seaweed to synthetic vascular grafts improves in situ endothelialization and could lead to better […]
Small molecule shows promise in treating temporal lobe epilepsy
BioTechniques News Beatrice Bowlby A novel drug candidate to treat temporal lobe epilepsy (TLE) has been identified, which suppresses TLE-induced neuroinflammation and […]
If you want to improve your cognitive abilities, learn piano
BioTechniques News Beatrice Bowlby Music training improves audio–visual processing and boosts your mood. Learning a musical instrument provides multisensory training, requiring you […]
Reinforcing cervical mucus: an alternative contraception method
BioTechniques News Aisha Al-Janabi Researchers have developed a topical, non-hormonal gel that can reinforce cervical mucus, acting as a barrier against sperm. […]
Finding Nemo: Using marine eDNA for biomonitoring
BioTechniques News Aisha Al-Janabi Using marine environmental DNA sampling, scientists identified more fish species than with conventional trawling techniques, but only if […]
Composition of gut microbiome drives granulopoiesis
BioTechniques News Aisha Al-Janabi Researchers demonstrate that changes in the intestinal microbiome stimulate neutrophil production in mice. Neutrophils are the most common […]
New Alzheimer’s drug is a cause for both optimism and caution
BioTechniques News Annie Coulson The full data for the Phase III trial of lecanemab has been published, showing that the drug slows […]
Infographic: Common challenges in cell-line development
BioTechniques News Beatrice Bowlby Cell-line development (CLD), from identifying a biological target to commercially manufacturing a biologic, is a long process and […]
2022 BioTechniques holiday gift guide
BioTechniques News Beatrice Bowlby Somehow, it’s the festive season once more, Secret Santas have been decided, office parties have been planned and […]
Targeting the link between PTSD and alcohol use disorder
BioTechniques News Aisha Al-Janabi Individuals with post-traumatic stress disorder (PTSD) are more likely to develop alcohol use disorder (AUD). Now, meet the […]
Could microRNA expansion explain octopus brain development?
BioTechniques News Beatrice Bowlby Scientists have demonstrated that cephalopods have an expanded number of microRNA families, which could explain how the complex […]
Fine-tuning synthetic protein production with CRISPR
BioTechniques News Aisha Al-Janabi Researchers have developed a novel method for controlling the precise amount of protein produced by mammalian cells. A […]
Could tumor matrix changes help explain lung cancer prognosis?
BioTechniques News Aisha Al-Janabi Scientists have shown that changes in the tumor matrix surrounding squamous cell carcinomas differ between patients with better […]